The Ohio State University at Newark


Dogan Ekici to Discuss Targeted Therapy as Cancer Treatment

NEWARK, OH, April 20, 2017 — Over the past decade, cancer treatments have significantly evolved into targeted therapies that are much better tolerated than traditional chemotherapy. Treatments known as small molecule inhibitors are drugs that interfere with the function of a specific biomolecule in cancer cells, hence altering the progression of cancer. The Ohio State University at Newark Assistant Professor of Chemistry and Biochemistry Özlem Doğan Ekici will discuss the development of small molecule inhibitors for a validated anticancer target known as the proteasome during an upcoming Faculty Talks Outside the Box lecture.

Doğan Ekici’s lecture will be held on Friday, May 5, 2017 at noon in the Norman R. and Althea E. Sleight Room located in the John L. and Christine Warner Library and Student Center, 1219 University Drive, Newark, Ohio 43055.

Doğan Ekici conducts drug discovery research which could extend or save the lives of those suffering from multiple myeloma. Multiple myeloma is a blood cancer that develops in the plasma cells found in bone marrow.

“Specifically we focus on making inhibitors for the 20S proteasome, which is a validated multiple myeloma target,” said Doğan Ekici. “If you block the activity of the proteasome, you actually block the tumor cells from proliferating. That slows the onset of the disease.”

Doğan Ekici was born and raised in Istanbul, Turkey. She received her bachelor’s degree in chemistry from Boğaziçi University in Istanbul in 1998 and moved to the United States the same year. She earned her doctorate in organic chemistry at the Georgia Institute of Technology in 2003. Dogan Ekici teaches an introduction to chemistry class on the Newark campus where she recruits future research assistants.

The Ohio State University at Newark offers an academic environment that’s challenging but supportive with world-renowned professors and access to Ohio State’s more than 200 majors. It’s where learning comes to life. Research, study abroad and service learning opportunities prepare students for their careers in ways they never expected.